Hi Jo, just my thoughts having done 2 clinical trials at the Royal Marsden, one successful, one not. Find out what phase the trial is at. Phase 1 is an escalating dose on a few patients at a time, looking mainly for drug tolerance. If you are right at the start the dose may be too small to be effective for you. Phases 2 and 3 are expansion ones where they have already ascertained effective doses. Ask what success they have had so far in % terms. How many have dropped out due to progression or intolerable side effects. Be aware of how much monitoring you will have as it can be fairly intense. In your shoes I would probably go for it once you have thrashed out the above. Wishing you the very best.
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