I’m doing fortnightly EC and have been using prolon fast mimicking diet which is marketed in the US as chemolieve. There are animal studies showing efficacy of FMD in decreasing side effects and improving tumour response. There is a recent study which suggested FMD may prevent need for dexamethasone https://www.nature.com/articles/s41467-020-16138-3, but there wasn’t sufficient evidence to prove efficacy the data did suggest further research required and promising. FMD is £190 so not cheap there are probably DIY options online but not scientifically trialled ones. The other suggestion is 48 hours of pure fasting but this could be adverse for people who are low weight, struggling with bone marrow supression or have underlying conditions like diabetes. I did 4 days including day of first cycle, and 3 days including day of 2nd cycle. I had a week of feeling rough but functional and then a week of normality including full return to normal sport. It’s hard to know if this was due to FMD or not, but I feel now I need to continue. When I switch to weekly PC I’m not sure how to do it, perhaps try 36 hours of fasting or 2 days of FMD. I am hoping to decrease my dex for next EC cycle as I have terrible insomnia on it. But my understanding is that on PC they insist on dex to prevent hypersensitivity reactions. Most important thing is to check with your oncology team if they known about fasting and if it is suitable to you as an individual good luck!
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