I had surgery to remove small tumour 3 weeks ago and was started on generic Letrozole last week prior to getting radiotherapy. After 3 days I got a rash on the affected breast. The next day the rash had spread to my neck and a day later covered most of my body. MacMillan Hotline suggested I stop the Letrozole and go to A&E to be checked and I was told it was a mild allergic reaction and to take anti-histamine. The next day I was concerned because my face was swelling. GP Surgery advised going to Urgent Care and the GP there gave me a prescription for a different anti-histamine. It is now 7 days since my first Letrozole and I still have a swollen face, although the rash on my body is starting to fade, and I only took it for 4 days. I am trying to work out what might be the ingredient causing this while waiting for a decision on next treatment but there is little information on allergic reactions to aromatase inhibitors.
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