Breast Cancer Now Forum

Maggie09 · ‎04-11-2014

Thanks for replies. I have switched from Letrozole to Tamoxifen. Think the extreme post-menopausal effects, including dry vagina and loss of libido are less. And it's not as bad for your bones. Had my annual follow up where I was told a different aromatase inhibitor would have been their second choice, presumably in terms of keeping cancer at bay. But I feel better and will take my chances on that.

Maggie09 · ‎08-09-2014

Thanks - another advantage of Tamoxifen, that it is OK to use topical oestrogen if needed.

Maggie09 · ‎02-09-2014

Thanks, I think I will try Tamoxifen instead of AI. Will share my experiences, hopefully should know one way of the other by Christmas!

Maggie09 · ‎31-08-2014

I had loss of libido (no desire for sex, no orgasms) on Letrozole; symptoms improved when I stopped for 2 months and returned when I restarted so I am sure it is that, not just being postmenopausal. I have been offered Exemestane (Aromasin) or Tamoxifen as alternatives (or of course I could stop taking anything and increase the risk of recurrence/death). Anyone got any suggestions as to which anti-oestrogens have least effect on libido? Thanks.

Breast Cancer Now Forum

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loss of libido - which antihormone therapy is best...