I can also access research online at a university and I found several papers on how L carnitine can reduce fatigue and boost mood among cancer patients. Most cancer patients are deficient in L carnitine and the research listed below all say that supplementation reduces fatigue – and improves mood. Safety, Tolerability and Symptom Outcomes Associated with l-Carnitine Supplementation in Patients with Cancer, Fatigue, and Carnitine Deficiency: A Phase I/II Study in the Journal of Pain and Symptom Management. http://www.sciencedirect.com/science/article/pii/S0885392406005549 The conclusion said “Most of the patients who received l-carnitine experienced improved fatigue, mood, and sleep.” l-carnitine supplementation for the treatment of fatigue and depressed mood in cancer patients with carnitine deficiency Ann NY Acad Sci, 1033 (2004), pp. 168–176 http://onlinelibrary.wiley.com/doi/10.1196/annals.1320.016/abstract This showed that supplementation did reduce fatigue – and also depression. Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic patients Br J Cancer, 86 (2002), pp. 1854–1857 http://www.nature.com/bjc/journal/v86/n12/full/6600413a.html This paper looked at whether L-carnitine improved fatigue among chemotherapy patients and concluded it did – after one week, fatigue lessened among 45 out of 50 patients . Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy – This concluded that L-carnitine did reduce fatigue. http://www.sciencedirect.com/science/article/pii/S0899900705002613 I also found a systematic review (the highest standard of research) into how L acetyl carnitine can reduce nerve pain/neuropathy with acceptable safety. Acetyl-L-Carnitine in the Treatment of Peripheral Neuropathic Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119479 I accept you can find evidence to the contrary but there is always contradictory evidence in medicine and it’s up to you to decide. However, this supplement is non-toxic and it worked for me so if you try it for a few weeks (when you should see an improvement), you haven’t got much to lose.
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