I was on tamoxifen for 4 years and started getting terrible right calf pain, tightness, for a period of 6 months. During that time because of the tightness I tore both the gastric and solcus muscles in my calf because of the tightness.I went off the tamoxifen and within 10 days the tightness and pain stopped and has not come back. My oncologist said it was doubtful that the tamoxifen was causing the tightness, after 4 years on the drug. He said if there was to be a side effect it would of started sooner. I proved him WRONG. He did however give his blessing for me to stay off the tamoxifen as I had been on it for 4 and a half years. I am still going thru physical therapy to stretch my calf muscles from all the damage the drug did. It has been 2 months now since I went off the tamoxifen and the pain, tightness in my calf has not come back.
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