I’ve been on Letrozole for four months, and found it impacted my mobility, to the extent that every part of me felt arthritic and painful, and basic tasks like getting dressed required all sorts of strategies to accomplish. I looked back at my meds and realised I’d been dispensed a different brand of Letrozole every month, so have recently asked my pharmacist to stick to one brand, which seems to have much fewer side effects for me.