@nib32 Yup, best descriptor ever. I took quite strong painkillers and antihistamine and omeprazole and drank Gavisocon. It us evil and is every infusion, sorry. I had 6 lots of the fecker and my chest was wrecked with it until the magic 4 above - took until the 3rd round to get med mix for me right!
Are they giving you an antihistamine infusion before the dose? I had 30mins on antihistamine infusion after first round being evil. Antihistamine then docetaxel then cyclophosphamide…
My dose was reduced only due to the mega reaction on day 10 - edema, hands split, hives, swelling lips … bleugh. Dose dropped to 80% - SE seriously reduced 
I was worst case scenario - cummulative effects kickd my arse.
Hope that helps
Karen x