A trial looking at a test to predict who might benefit from chemotherapy for breast cancer (OPTIMA)

The aim of this trial is to see if it is safe and effective to use a test like Prosigna to choose treatment.  

More info on this link.

You may be able to enter this trial if your breast cancer:

  • Had grown into the surrounding healthy tissue (invasive breast cancer)
  • Has been removed with surgery

And you are in one of the following situations:

  • 1 to 9 lymph nodes under your arm have cancer in them. If your cancer has spread to only 1 to 3 lymph nodes, at least in 1 node the spread is greater than 2mm across
  • Your cancer measured more than 20mm, it has spread to 1 to 3 lymph nodes  and is less than 2mm across in each node
  • Your cancer measured 30mm or more but had not spread to the lymph nodes

And all of the following apply:

  • Your cancer is oestrogen receptor positive
  • Your cancer is HER 2 negative
  • You are able to have chemotherapy after your surgery
  • You are at least 40 years old

Find more information on this page.

Chief investigator: Dr Rob Stein

Recruitment ends: 31 Dec 2021