Pins and needles in hands and feet isn’t listed as a side effect on the amaciclib leaflet. But has anyone experienced this, and been told by their oncologist that it is an effect please?
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Hi @hedera , welcome to the forum,I’m sorry you haven’t had a reply to your post yet .You could maybe ask about this in the Ask our Nurses your questions sectio of the forum for some advice ?
Hi Hedera,
I started to take Abemaciclib at the end of April 2024 alongside letrozole which I started in December 2023. I have stayed on the 150mg dose as the diarrhoea and abdominal pain settled in a couple of months and my bloods have been pretty much ok. I have found more recently that my fingertips do have a sensation which is a sort of cross between numbness and pins and needles, my feet not really.
In the last month or so I have noticed my nails becoming brittle, my hair thinning, skin itching and very dry, a bit of neuropathy in my big toes. Nothing unbearable and I wear roomy shoes, keep moving, stay hydrated and use lots of moisturiser!
What I don’t know is how it’s going to be as time goes on and also what may be due to the letrozole rather than the Abemaciclib.
At 70 yrs I had considered myself pretty much an oestrogen free zone but my little grade 3 cancer was 100% loving oestrogen. I did get a revisitation of hot flushes after starting the letrozole, but not as much I had had between age 55-65…
Anyway, I’m reminded of how I was in the last few weeks of paclitaxel with the skin and the toe pain- toes were so sore I went down to 80% dose after week 7. My skin was dry and after the course finished it actually got got worse, with psoriasis patches developing! The weekly paclitaxel had felt much more tolerable for me than the 4 sessions of E/C that had preceded it
So I started the Abemaciclib with very thick fuzzy short hair reasonable skin and good nails on fingers and toes as in spite of the lymph node clearance in December and Radiotherapy throughout March things did recover. Currently the hair thinning is quite welcome, but I’m wondering how it will be in 17 months time!
I am glad to have this treatment, though I had been appalled when I read the leaflet which the oncologist gave me back in December!
So, how are you doing now, well I hope! I would be interested to hear how you’re doing as time goes on with this treatment- and from anyone else as they continue with the prescription.
All the very best to you Hedera,
Cynoptimistic