Abemaciclib stopped due to drop in GFR

Hi everyone can I ask if anyone has had to have their medication stopped due to abnormal bloods. I recently 24th June had Covid, again, which made me unwell for a couple of days. So my recent bloods have shown that my kidney function GFR has dropped from 96 to 55, so unfortunately again I can’t have my medication. I’m concerned that I’ve not taken my meds and now I have poorly functioning kidneys. Has anyone been in this situation and what was the outcome/plan? I’m feeling very anxious and frightened once again

Hi @Gemini111 , I am sorry to read you are feeling frightened.

Would it help to speak to one of our team of breast care nurses? You can reach us on freephone 0808 800 6000 (Mon-Fri 9am-4pm; Sat 9am-1pm). You can ask anything you want, and we’ll go through things at your own pace. Our nurses answer thousands of questions every year, so please do not hesitate to pick up the phone and get in touch.

Sending sunshine and positive energy your way


Hello! I was on Abemaciclib but my liver function went haywire so I had to come off it. Had a long period of not being on any treatment which was scary but I’m now on cape and I’ve had no problems with it so far. Sending you hugs xx


I had my treatment stopped for a week due to Covid then once I tested negative went to get bloods done to start again and my liver levels weren’t right. This had never happened before and after a bit of uncertainty everyone agreed it was an effect of Covid. One week later they had returned to normal and I was back on my plan. 
I was incredibly anxious with it all. I had had a weeks delay before due to low neutrophils but two weeks off was more than I could cope with. However everything seemed to go back to ‘normal’ again once I was back on it. 
Hopefully this will be the same for you and your bloods will soon settle