About two weeks or so ago I posted on here about my ALP levels rising. I retested yesterday and they are a little higher still for the first time in the abnormal range. (121 was highest normal and I was 129). It was at a different lab than last time but I think it’s clear now that ALP levels are definitely rising and there is a reason. I know it can be bone mets and obviously that’s my worst fear. But I also know they can rise in menopause due to just degenerative bone loss. I had a dexa scan last year and I wasn’t classified as osteopenia because I didn’t classify myself as post menopausal. But I was and am. And the osteopenia wasn’t mild. Two of my bones were over -2 so approaching osteoporosis numbers. Has anybody had experience with ALP levels rising after going on AI’s? If so, why, and how did you fix it? I am trying not to panic but it’s hard. I’ve got an e-mail out to my oncologist’s office but haven’t heard back. I do not want a bone scan since I’m asymptomatic so I’m hoping that’s not suggested. Thank you for your help!!
Hi, I am reading this post with interest as I was diagnosed with bc may 24, with lymph node involvement I have been on letrezole for a while and my alp is at 239 and going up, I had a ct scan a couple of weeks ago and waiting for results but am terrified that it’s spread to my liver.
I am so sorry you’re going through the dreaded ALP rising numbers game. I will remind you that ALP numbers are not a cancer marker in and by themselves. They can suggest something is going on but that’s it. And what is going on is normally very different than cancer. Some of the things to look at are ALT and AST. Are they normal? Then your rising ALP numbers will probably not have much to do with your liver. For me it was my bones losing mass. Once I went on biophosphonate infusions they stabilized and went back down. They’ll probably rise again when I stop the infusions but at least I’ll know what it is then. So it reads like your doctors are doing a good thing by following up but remember the chances are really good it’s something else.
Hi thank you for that, it’s good to know it’s definitive, I had a bone density scan a while ago so I think that side is okay, my serum gamma is also quite high, as well as the inflammation markers, it’s all such a worry. And it’s hard waiting for results
I know. I’m so sorry you’re playing the waiting game right now. If it’s any comfort I plugged in what you said here to ChatGPT and it said that fatty liver issues, bile flow issues or medication issues are the most likely culprit. In other words, not cancer.
Thank you for that, I need to figure out how to use chat gp lol.
Just go to the site and type in your questions. It’s a great resource but just remember it’s not a substitution for doctors or sound medical advice. It is prone to errors depending on how you use it. But I love it. It makes researching so easy and I’m a big one for researching.