Alternatives to Letrozole?

Hi Ladies

I’ve been on letrozole for a year now, and finding the tiredness quite hard to cope with at times. What are the alternatives to letrozole, and what side effects do they have?

Thanks

Sue xx

Hello sue
If u want to stay on hormones the choices are:
Tamoxifen
Anastrozole ( arimidex )
Exmestance

Don’t know about anything else but Exmestance seems to be kinder from what I’ve read on the threads but I have no experience as I’m a letrozole (accord brand only) girl.
I don’t think any of them are free of side effects to be honest but it getting the one that is the least! !!
Showing off but I did 2 years on tamoxifen and 3 years on arimidex at primary stage …apart from hot flush didn’t notice much problem but I was only 51 and fit and active then.

Thanks Carolyn

I’m also on accord, so can’t change anything there. I was wondering if letrozole is more effective than the others? Why is letrozole the standard med to start with? 

Reading up on side effectives, there doesn’t seem much in it.

Sue xx

I think I read that in a clinical trial years ago …letrozole was superior to the others but not sure really. It’s controlled my extensive bone mets now for 2 years so I’m very thankful of this little pill.
If u are really struggling …maybe a chat to your oncologist about Exmestance which is the newer kid on the block used more now as it’s out of licence and compares price wise to the others .
It’s also used in conjunction with an affinator for ladies with secondaries and can be very efficient.
Hugs xx