Anastrozole: Morning or night?

Hi all. I’ve been taking Anastrozole for nearly 3 months and seem to tolerate it quite well…except for sleep!!! I used to be able to put the light out and fall asleep fairly quickly. Ok I’d have the occasional night when I couldn’t get to sleep but nothing like now. 

I lie there for at least 2 hours tossing and turning. I’ve tried all the usual remedies without success. I take the drug in morning after breakfast so I’m now thinking maybe I should take it last thing at night. 

Be interested to know if anyone else has had this problem and if changing the time you took the pill helped. 

Hope all are doing well, 

Pat xx :cathappy:

Hi pat, I’m in similar quandary. I take mine in the morning like you. Not having any major side affects but I don’t sleep very well either. Don’t want to feel sleep the next day though. Maybe someone on here  can advise. 

All the best, Sue 

Hi. I’ve only been taking for 3 weeks. My oncologist advised me to take it ar night, as it can make you nauseous. It very definitely did! That side effect seems to be wearing off now but I’ve stuck with bedtime. I am more wakeful than before and definitely more flashes and flushes. It’s difficult to know if it’s the meds or rads but I’m very tired in the afternoons. Will be good to hear from others also x

Thanks Sue and Janey. 

I didn’t take it this morning and am going to take it last thing tonight in hope I get to sleep better! I will report outcome of experiment tomorrow! :cattongue:

I don’t seem to be having many other side effects. I’ve had a few hot flushes at first but they seem to have gone and I’ve got some joint pain but not too bad…BUT might be because I take Amitriptyline for MS pain anyway…and that’s the same drug recommended for joint pain from Anastrozole. Bit of luck that I’ve been taking it for a few years. :womanhappy:

Hugs to all, 

Pat xx 

Hello, nice to hear from you.  Sorry to hear you too are suffering from sleep deprivation from Anastrozole.  Please let us know how you get on changing to taking it at night rather than the morning.  I think we both started taking it about the same time? End of June?  I’m currently two and a half weeks into a six week break from it. I was suffering horrendous sweets/flushes plus aches and pains (though these are bearable so far)  and insomnia.  Oncologist said my body could not tolerate it and to stop it.  I was very concerned about stopping and after speaking to BCN we decided I need to have a break in order to get some sleep and recover From Rads then start again.  Since stopping, flushes and sweats have not improved, however, I do drop off to sleep inbetween them so am getting an hour sweating, twenty minutes cool down, approx hours sleep then start all over.  When I was taking Anastrozole I used to drop off ok then wake with a jolt, sweats would start then that was it sleep wise.  I guess sweats/flushes are then menopause and not all down to pills (came off hrt at same time as starting pills) aches and pains havent mproved yet.

 

Pat, how are you generally?  I know you have ms to deal with ontop of all this BC stuff.  You were such a support to us having rads in July/August.  Have you recovered from them yet?  I’m still suffering skin problems  which I didn’t expect as skin held up fine until the end, just got worse and worse after.  Hope you’re not having any such problems, you’ve got enough to deal with.  Xx

Morning! It seems worthwhile experimenting. I’m not sure whether to be optimistic, or whether it’s a side effect of the rads. However, I’ve been taking evening primrose for ages and I’d read on the site that some people were advised to take it alongside the Anastrozole. So yesterday I took it at bed time with the Anastrozole and I slept through till 7. I’m hoping it’s not a fluke and do think it may be rads tiredness but I’m going to do the same tonight and double check. I haven’t slept through for 5 years, I hope I haven’t been missing a trick!! Our reactions seem to be so varied. Will let you know what happens. Hugs xx

Nooooo! Tuesday night was a sleep I shall cherish but last night back to my normal. I’m going to persevere for a week. I am starting to feel increasingly tired as I go through treatment, so hoping to get some respite and sleep. Happy Thursday! Xx