So bone mets was not exactly great news, but I was accepted on to the trial for Palbociclib with Letrazole, and completed the first cycle OK - or so I thought until the routine blood tests showed really low neutrophils (.86 with a threshold of 1.0). Never mind, they said, continue with the Letrazole, have the denosumab which is also due, and we can give you Palbociclib next week when your blood count has improved. Unfortunately, it went down instead of up (.81), so they’re leaving me another week…hence my question: Does anyone have any ideas for increasing my white cell count by next Friday? The associated question is that although Palbociclib has a reputation for neutropenia, (probably why they only give it for 3 weeks out of every 4), does anyone know of a similar effect from denosumab/xgeva? I’m curious because this would explain why the count was lower 2 weeks after the last tablet of P than it was 1 week after it.
Hi Lizzie
Please do give our Helpline a call, they will be able to answer any questions or concerns you have.
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Best wishes
Anna
Digital Community Officer
Hi just wondered where the trial is for palbociclib?and if they are still accepting patients ?
The defaul tea drunk in my house is Earl Grey, just because I take milk, but my husband takes it black. It’s taken over a year for the penny to drop but the oil of bergamot which it contains comes from a shrub closely related to grapefruit and seville oranges. There’s no problem with other citrus fruits, but (as with some other prescription medicines) the patient guidelines clearly warn you not to have grapefruit with it. As soon as I stopped drinking Earl Grey my monthly neutrophil count rose, and my red cell count, which had never dropped below the threshold also improved.