Can I use Ovestin cream?

Hi everyone. In 2006 I had estrogen positive breast cancer and was on Tamoxifen for 10 years. Now nearly 18 years later I am suffering from vaginal atrophy, repeat UTIs and very painful penetrative sex. My GP referred me to a gynaecologist who prescribed me Hyalofemme daily, Yes VM and Ovestin 2x a week for 3 months along with using dilators.
I am ok using Hyalofemme, Yes VM and have started using the smallest dilator
But I am so scared to use Ovestin because in 2006 my oncologist said no estrogen products. My gynaecologist said opinions have changed and it is ok for BC survivors to use Ovestin. This gave me courage but when I read the Ovestin leaflet it says not to use if you have had BC…and the NHS website on Ovestin says not to use it either.
I am so confused…and scared to use it.

Is it safe to use if you have had BC?
Sorry for long post but I would appreciate your thoughts.

Hope this reassures you. I’m thinking about this too atm, though as I already have MBC the stakes are not so high for me!! All the best, but it sounds like current thinking is that it’s safe.

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Thank you so very much for this reassuring link. Thinking of you and sending hugs and good wishes.x

Hello yesnik,

Thank you for posting.

It sounds like you are having a difficult time with vaginal dryness and genitourinary symptoms. These can be distressing symptoms which can impact on quality of life and sexual intimacy..

We often hear from women who have had breast cancer and have been offered a course of hormonal treatment such as Ovestin to reduce and alleviate the symptoms they are experiencing. As you said it can be confusing and scary when reading the patient information.

The type of hormonal treatment you have been advised to use is a vaginal oestrogen. It contains a very low dose of oestrogen which is absorbed locally into the vaginal wall which is absorbed where it is applied. It can be considered if non hormonal treatments, such as vaginal lubricants and moisturisers, have not been helpful. Although 18 years ago your oncologist told you to avoid oestrogen creams, opinions have changed since then and as your gynaecologist explained the current use of vagina creams is evidence based.

Most importantly you are under the care of a specialist who knows you have had oestrogen receptor breast cancer and is familiar with recent guidance on vaginal hormone treatments and it sounds like they are treating you as an individual and that you have a plan going forward with your doctor. If you are still in any doubt, do contact your treatment team who cared for you or speak to your GP.

As @senga66 mentions in her post a recent the social media link on the use of vaginal oestrogens could provide you with some reassurance

You may also find some of the question and answer presentations that we have on the Breast Cancer Now YouTube channels about menopausal symptoms useful.

Do call our helpline if you would like to talk this through or have any further questions. The helpline team have time to listen, talk things through and signpost you to more support and information if necessary. Your call will be confidential, and the number is free from UK landlines and all mobile networks. The number is 0808 800 6000, (Relay UK - prefix 18001).

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Best wishes


Breast Care Nurse

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