Hello Everyone,
I am here on behalf of my wife (and at her request) to hopefully gain some insight and personal experiences from others here on this forum that have had or are currently having treatments using capecitabine as a mono-therapy for MBC in the bone.
My wife was diagnosed with MBC of the bone in Fall of 2022. She is ER+/HER2 Negative with ESR1 and PIK3CA mutations. Her treatment started in late 2022 with Kisqali (stopped due to neutropenia) then Verzenio (stopped due to neutropenia and progression) and then Oserdu (stopped due to progression). Her Oncologist has moved her to capecitabine (one week on, one week off regime) which she started this September, with her first PET/CT coming up mid December since starting the cape. Since the start of the cape she still has experienced on and off pain at the sites of her mets (sternum, ribs, scapula T-1 vert and a few other sites in the torso region, all bone). It’s difficult because we also know the cape can cause bone, muscle and joint pain so it’s really hard to tell at this point exactly what is causing the pains. We have read that a patients experience with pain from the cancer can often get worse before it gets better when taking chemo - has anyone here experienced that while taking capecitabine? We also read that with a slow going cancer (like my wife’s) the cape will take longer to work (or work slower) than one that has a fast growing cancer - again if anyone here has any insight / experience with this it would be immensely appreciated if you could share. Essentially at this point my wife is looking for any mental assurance and comfort as in a few shot weeks she will be in for her PET and we will. Know where things are at… hoping for the best with the cape, as she is tolerating it extremely well.
The best to all here.
Thank you in advance to anyone who can share
Pierre1