Elacestrant (Orserdu)

Hello . Has anyone any experience of being on Elacestrant ( orsedu)?
It is a new hormone treatment for advanced metastatic breast cancer , just authorised by NICE in the uk . It is for those people for whom a blood test shows that they have acquired a gene which makes the cancer cells resistant to hormone oestrogen blocking therapy. But it’s more likely to be the case if you have been on other hormone treatments a long time before they failed.
I was only on ribociclib / fulvestrant for just the qualifying time of a year before it failed so I may well not have the gene .

I am 76 and not just looking to extend my life on and on -life is declining but that’s ok . I am taking tamoxifen at the moment having declined toxic chemo and treatments as third line treatment.

I’m doing okay on tamoxifen In terms of how I feel, although there is no monitoring of it so my oncologist has no idea if it’s doing anything.

I think it may be unlikely that anybody else has much experience of this drug because it is just hot off the press so to speak after a small research study. My oncologist is very focused on research.

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Hi @Gillmary

Unfortunately I haven’t been able to find any other threads on the forum about elacestrant, but hopefully someone here has an experience they can share with you.

In the meantime, you may find our website information about the drug useful (although it sounds like you are very well informed): Elacestrant (Orserdu) | Breast Cancer Now.

Please also know that our nurses are here to support you - with clinical questions or for a chat. You can get in touch with them here on the forum on the Ask our Nurses your questions board or on our helpline 0808 800 6000 which is open Monday to Friday 9am-4pm and 9am-1pm Saturday.

Sending our warmest,
Lucy