my final pathology discovered two tumours. One is ER 8/8 PR 7/8 but the other is ER 6/8 PR 0/8. Both tumours 2cm, grade 2, lymph nodes clear. I am HER2-
I am waiting on Oncotype score due to the PR 0/8 - has anybody had a similar diagnosis and what was your preventative treatment please? Im obviously hoping to avoid chemo and start on hormone blockers, but not sure how much of a problem the PR 0/8 is. I know from research it would be better if it was also PR receptive, but just wondered if this has happened to anybody else and whether they still just had hormone blockers? Please no negative prognosis facts as Im already becoming pretty mentally unwell with the relentless stages of this journey. Thanks
My tumour was er 50% pr10% -pr low. My onco was high. They said it was possibly because of low pr. As a result I needed chemo. Im coming to the end of chemo. It was manageable. Oncologist told me the er is the key. Especially if its strong er, it should still be responsive to endocrine therapy such as tamoxifan.
Id advise stay away from google. Write any question you have around hormone receptors down and direct them to your team. It does seem to be an under researched combination of tumour.
Do you mind me asking when you found out about your hormone receptor status?
I had a mastectomy over three weeks ago and although they found a small 5mm area of IDC I still haven’t been told the status and I’m just wondering if this is unusual? I’ve since had my sentinel nodes removed on Friday and don’t know whether I should ask them sooner or wait till my results from that?
Before surgery I was told mine was er+ pr+ her2- but after mastectomy mine was er+ pr- her2-.
i am having chemotherapy at the moment for prevention but that was due to my onco score being high. No one’s told me it was because of being pr-.
I was never actually told mine had changed to pr- I read it on a letter on my nhs app. So at my oncology appointment I asked about it and she didn’t seem concerned. I’d read things before and it being a little worse so I was really worried but my oncologist didn’t seem worried so I feel a bit better.
I am having weekly paclitaxol for 12 weeks then move onto ec every 2 weeks for 8 weeks. Then 3 weeks radiotherapy then hormone blockers.
