Hello- I posted the message below in a forum. I’ve received no resonses. Can the nurses help with this query? Im also interested in knowing the steroidal impacts of the drug. Have their been studies on the impact of this drug on the women who take it? Where can i find the studies?
Orhinal post -
Hello. Thanks for those who have posted about Exemestane. Its been helpful to understand the experience of others. I was on Letrozole for just over a year. Overall I did ok on it but towards the year mark (Sept 2024) the joint pain was getting bad. I’ve had a break off it for 5 weeks. I should be starting Exemestane. I’m concerned that one of the common side effects is reduced white blood cells which could result in higher risk of infections. Has anyone experienced getting infections more since starting Exemestane? Thanks.
It’s understandable to have concerns about the side effects of Exemestane. The most common side effects are menopausal type symptoms such as hot flushes, joint pain and fatigue. As with any medication, it is important to be aware of any potential side effects. A reduction in white blood cells has been reported whilst taking exemestane, though this is more common in those with pre-existing problems with the immune system. The frequency of this side effect is not known from the available data (see page 4). Should you experience any signs of infection, its important report this to your GP or treatment team.
Many people experience joint pain on letrozole, and it is not uncommon for people to have to change to a different aromatase inhibitor. Although Exemestane is classed as a steroidal aromatase inhibitor, it works differently to other steroid medication. It selectively reduces oestrogen without impacting other levels of steroidal hormones produced by the body and so does not have the same side effects as many of the more common steroid medications. You may find it helpful to speak with your treatment team or GP about your concerns.
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