Facial sweating on anastrazole

Hello, I was diagnosed with primary breast cancer 5 years ago (ER+, HER2+, grade3). I had a mastectomy, chemotherapy, Trastuzumab /pertuzumab, bisphosphonates and I’m now on anastrazole for 10 years. I’m 56 and had gone through menopause before my diagnosis. I have noticed over the past several years that the slightest exertion (or just a warm day) makes my face, scalp and neck STREAM with sweat to the point where it is dripping off me. It is very embarrassing- yesterday I helped a neighbour assemble a piece of garden furniture and sweat was dripping off me onto the furniture :flushed: I’ve used an AI search to explore this, which suggests it’s down to suppression of oestrogen which affects body temperature regulation. Is this right? Is there anything I can do to improve things (or do I just need a permanent sports towel round my neck)?? I’m trying to improve my fitness through gentle running and strength training - I feel like I’m losing litres! Any advice would be gratefully received, thank you.

Hi. I am also on Anastrazole for 5 years. I am 3.5 years into it and am having exactly the same problem. Yes it is horrible and the slightest thing sets it off and is even worse when weather is hot. I would also like to know if there is anything that can help although I suspect there isn’t.

Jayne

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Same for me - weirdly, the rest of my body doesn’t sweat to an unusual degree, just face, head and neck. No idea why it’s so localised! :woman_shrugging: I’m so sorry you are suffering too - hopefully we (and others) now know we are not alone :heartbeat:

Hi sissy1

Thank you for your post asking about the side effects of anastrozole and if there is anything that might help.

It sounds like you have been having a difficult time with hot flushes and sweats. Hormone therapies such as anastrozole block or stop the effect of oestrogen on breast cancer cells. This can cause menopausal symptoms, including hot flushes and sweats.

Many women contact us describing the difficulties they are experiencing with menopausal symptoms, such as hot flushes, as @Jaynie23 mentions. For many women they will fade over time and become less severe, but for some they may continue to experience hot flushes and sweats which can really affect their quality of life. A hot flush can range from a mild sensation of warming which just affects the face, to waves of heat throughout the body. Some women also experience a drenching sweat affecting the entire body.

We know that there are different things that help with hot flushes. You can speak with your breast care nurse or treatment team to discuss possible options for managing hot flushes. These are discussed in the link. Your GP may also be able to help. You may want to ask about a referral to specialist menopause clinic where you can get further information and support about coping with menopausal symptoms.

Some people find certain complementary therapies can help as well. You may find this section of our forum around hormone therapy helpful to reach out to others who may be experiencing the same side effect and ask what has helped them.

You mention you are trying to improve your fitness. You may find our information on physical activity and exercise useful.

Do also call our helpline if you would like to talk this through or have any further questions. The helpline team have time to listen, talk things through and signpost you to additional support and information if necessary. Your call will be confidential, and the number is free from UK landlines and all mobile networks.

The number is 0808 800 6000. If you have hearing or speech difficulties prefix our number with 18001 and the call will go through Relay UK. Our helpline has access to telephone interpreters if language translation is required.

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Best wishes

Teresa

Breast Care Nurse

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