For those interested in research on diet and cancer

Public Archive
1001

Thanks for the warm welcome. Much appreciated :slight_smile:

About to dash out for the day, so this is just a quick post about a free electronic breast cancer medical journal called ā€˜Artemisā€™ produced by the Johns Hopkins Breast Centre - so a reliable source. It gives an easy-to-understand monthly round-up of research, which also covers research concerning food.

Just in case not everybody has heard about it. You can ā€˜subscribeā€™ to have the link emailed to you whenever a new edition is ready.

Hereā€™s a link to the June edition, which has an interesting piece of research about parsley and celery
hopkinsbreastcenter.org/artemis/

KL

1002

Hi everyone,
Great to see everyones different views on all these issues,and of course at the end of the day we can all do our own research and do what feel right for us personaly even if some of the current evidence is lacking, its a good thing if nothing else to get back some control in our lives.

Hi Elinda,
Im not sure what you were told from your friends/onc in Canada is reccommended in all Canadian hospitals i think it likely varies quite a bit depending on the hospital ,
I have quite a few relatives in Canada (lovely Country)and they tell me the reccommended daily allowance is 600 IU of Vitamin D for adults,not sure if this is correct but i checked it with Canada Health and it seems to be right.

The U.S. Institute of Medicine (IOM) released its report on the review of the Dietary Reference Intakes (DRIs) for vitamin D and calcium on November 30, 2010. The review was jointly commissioned and funded by the U.S. and Canadian governments.

hc-sc.gc.ca/fn-an/nutrition/vitamin/vita-d-eng.php

Also at the same time Nov/10, the AICR published the joint reccommendations for Vitamin D for Cancer.

blog.aicr.org/2010/11/30/vitamin-d-for-cancer-prevention-no-supplements-needed/

Like everyones says its up to each of us to wade through the info and come to own conclusions, but good also to get the current reccomended guidelines from all the different countries in making our decisions.
Must be realy baffleing especialy for any newly DX ladies who might be reading all the conflicting stuff online.

Hope you are all keeping well.
Linda x

1003

KL, do you realise you have completely blown any chance of me doing any work this afternoon?

What an excellent link, thanks!

1004

Johns Hopkins is brilliant , thanks KL its a great sorce of information for Cancer Patients, its amongst one of the best cancer centers in the world.
x

1005

Another interesting new study adding to the evidence about breast cancer and low glucose / insulin diets. Itā€™s in mice, but the survival differences in comparing a western diet to a low carb/sugar diet are striking:

foodforbreastcancer.com/news/low-carbohydrate%2c-high-protein-diet-inhibits-mammary-tumor-growth-and-development-in-mice

1006

Hi All wow so much to catch up oh
Hi Linda your welcome & yes your right Vit D being fat soluble it takes a while too for the levels to build up in the body, anyone supplimenting may not get the full benifits for several weeks. It is very hard to over dose with it as alot of whats not absorbed leaves the body in the natural ways.

Good point about testing during the winter ā€¦ Ill have to consider the purse strings but may feel it worth while doing again this winter if anything to keep an eye on the levels/ amounts to take ā€¦ my onc never advised me he said they are not allowed to but if I want to take it that was down to me, but he did comment on what he had read about it & studies he had seen ā€¦ same as with the calcium & Omega 3 LOL it must be quite difficult for them cant comment yet anyone like me that fires 20 questions each time I think he dreads seeing me lol I did push it a bit when asking about the suppliments & he got the low down on my diet & all my own research but all he said was his veiws & I seemed to have my head screwed on there was nothing he said NOT to take of what I was taking he even kept a copy I gave him in my file :slight_smile: he knew all about curcumin & knew about mixing the termeric with black pepper & small amount of olive oil before adding to meals if you have it this way. I like it this way but the family not keen !

Mekala x

1007

Hi KL you have a good onc thats great when they are open minded & work well with you, I like mine he seems to take all the presure off my worries & I feel confident that he is doing what is needed now, whereas at 1st I was a bit concerned if I was being under treated, what I thought was great was second time of seeing him I bumped into him in the hospital coridor & he remembered my name straight away with a nice good morning Mekala & he is head of oncology for our area covering all the hospitals. Canā€™t be bad when they make you feel like a person & not just another cancer patient.

Hi Finty it does speak volumes the ā€˜western dietā€™ :frowning: we are so unhealthy compared to those on asian & mediteranean diets

1008

The internet is clearly keeping us all busy - thanks so much for links.
Am still working on the glucose idea and have come across Simonciniā€™s work with cancer and candida and sodium bicarbonate. Itā€™s controversial but this study is academically reported.

curenaturalicancro.com

"Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases
Published Online First on March 10, 2009
Research by:
Arizona Cancer Center, University of Arizona, Tucson, Arizona
Department of Pharmacology, Wayne State University, Detroit, Michigan
H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
Ian F. Robey, Brenda K. Baggett, Nathaniel D. Kirkpatrick, Denise J. Roe, Julie Dosescu, Bonnie F. Sloane, Arig Ibrahim Hashim, David L. Morse, Natarajan Raghunand, Robert A. Gatenby, and Robert J. Gillies

Abstract
The external pH of solid tumors is acidic as a consequence of increased metabolism of glucose and poor perfusion. Acid pH has been shown to stimulate tumor cell invasion and metastasis in vitro and in cells before tail vein injection in vivo. The present study investigates whether inhibition of this tumor acidity will reduce the incidence of in vivo metastases.
They show that oral NaHCO3 selectively increased the pH of tumors and reduced the formation of spontaneous metastases in mouse models of metastatic breast cancer. This treatment regimen was shown to significantly increase the extracellular pH, but not the intracellular pH, of tumors by 31P magnetic resonance spectroscopy and the export of acid from growing tumors by fluorescence microscopy of tumors grown in window chambers.
NaHCO3 therapy also reduced the rate of lymph node involvement, yet did not affect the levels of circulating tumor cells, suggesting that reduced organ metastases were not due to increased intravasation.

In contrast, NaHCO3 therapy significantly reduced the formation of hepatic metastases following intrasplenic injection, suggesting that it did inhibit extravasation and colonization. In tail vein injections of alternative cancer models, bicarbonate had mixed results, inhibiting the formation of metastases from PC3M prostate cancer cells, but not those of B16 melanoma. Although the mechanism of this therapy is not known with certainty, low pH was shown to increase the release of active cathepsin B, an important matrix remodeling protease.
Source: Cancer Res 2009;69(6):2260ā€“8 | PMID: 19276390 [PubMed - in process]

Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases This article has been published by the AACR"

Not sure myself of the ā€œcureā€ he proposes but the candida link interests me as I had chronic fatique several times in the 20 years before BC hit me and candida/fungus has often been linked to that.
Anyway ā€œmore food for thoughtā€ - seems an appropriate metaphor for this discussion forum!

Thanks BT for info on grapefruit - think itā€™s off the menu nowā€¦but oranges, in moderation, remain.
Fran

1009

KL - thanks so much for John Hopkins link - my breakfast veg stir-fry on my menu for the last year always includes celery and I also pick fresh parsley to have with it - will continue to do so and think positive thoughts!

1010

Mekala - I posted the sweet potato recipes on the other thread along with Turmeric rice, this might get them to eat it!

DaisyGirl xx

1011

Hi francesw,

Just thought it might be wise to post a word of caution for everyone here about the doctor whoā€™s theories included baking soda to shrink tumors. He lost his license to practice medicine in 2003 in Italy.

Cancer is not a Fungus

123hjemmeside.dk/cancer_is_not_a_fungus/21160724

ā€œIt is easy to find testimonials on the internet, praising his approach. But reports of actual harm caused by acceptance of his ideas are still surfacing.ā€

123hjemmeside.dk/cancer_is_not_a_fungus/21160738

I know we covered this topic on the Wacky thread a few mths back so not sure if youve already read about it,but i think it would be proberly very wise for anyone to steer well clear of this particular fellow.

Hope you dont mind me bringing this to everyones attension ,but unfortunately some of the stuff online can be pretty dangerous.

Linda x

1012

Thanks CG for info - I know heā€™s very controversial but the research paper is academicā€¦
I know cancer is not a fungus but my view is that a fungal infection can reduce immunity so could be linked???
Thanks for sharing - we need all info we can get in trying to work out appropriate diet individually.

1013

Thankyou Daisygirl I go hunt that out :slight_smile: finty I use celery & fresh parsley in stir fry but not for breakfast its a lovely combination
KL thanks ever so for the link great website

thanks Linda for the link I remember reading on a site a long while back a husband giving his wife capsules filled with baking soda for her lung tumor every morning & thought it strange at the time, not something id consider doing or ever looked into baking soda is great for getting tea stains off cups & stainless steal :smiley:

1014

Just remembered that bicarbonate of soda sorted out my cystitis on several occasions years ago ā€¦ it does help with acidityā€¦

1015

Hi Ladies,
Your very welcome, its great to share all the info we find with each other sometimes as i think it does help us to make those decisions which are important and right for each of us .

Best Wishes
Linda x

1016

Mekala - I am just about to tuck into Moroccan Stew, absolutely delish! Hope you enjoy it too!

DaisyGirl xx

1017

Been out for the day and thereā€™s just so much to catch up on!

Karen - as Finty has said, BCC states we are not allowed to recommend any dosages. The Onc didnā€™t actually tell me a dosage and I had too many things on my mind at the time to ask. Iā€™ve seen a different one since and I havenā€™t asked him about Vit D.
I made my own decision on dosage based on the research I posted. I donā€™t supplement anything else and I donā€™t take it when I can get sunshine.

Kentishlass - great that youā€™ve joined the thread! Thank you for your kind words. I couldnā€™t agree more with your sentiments diet. I also agree that looking at my diet has made me expand what I eat rather than limit it.

Bicarb of soda - personally, I wouldnā€™t take it. Itā€™s a very powerful thing and I think could be quite dangerous.

Iā€™ll have a good read through of the research links youā€™ve been posting tomorrow. Elinda x

1018

Also re dosing, the RDA for Vit D (200IU) is much lower than that required to get serum Vit D levels in the range that has been associated with a reduced breast cancer risk. The study of 4000 odd people that I linked to established that a daily dose of 1000 - 4000 IU was required to get serum Vit D levels high enough to be in the reduced risk group, and that levels rise so slowly that even supplementing 10,000 a day only rarely puts you at the lower range for possible toxicity. So on this occasion I donā€™t think RDAs are relevant.

1019

Hi finty,
Did you read the new reccommendations with the review of all the research as to why RDAs have now been changed? they now know after the review of all the data that there is no additional beneifit in suppliementing Vitamin d in excessive amounts.
The links of how the IOM have come to this conclusion are at the bottom of Heath Canadas webpage Link i think one link also refers to serum Vit D levels.

I quess its up to each individual to decide for themselves,but the current data clearly shows theres is no added benifit in exceeding the RDAs.

I quess we all have to weigh up benifit vrs risks.

Linda

1020

Hi everyone,
Looks like after the review of the current data and the new RDAs of Vitamin d were announced by the IOM CRUK has also Published their own ā€œJoint position statement issued to provide vitamin D clarity .ā€

info.cancerresearchuk.org/news/archive/cancernews/2010-12-16-Joint-position-statement-issued-to-provide-vitamin-D-clarity-

The Consensus Vitamin D position statement is below.

info.cancerresearchuk.org/prod_consump/groups/cr_common/@nre/@sun/documents/generalcontent/cr_052628.pdf

CRUKs statement seems to go into a bit more detail about the current findings, but it certainly looks to be the consensus view of all three countries at at the moment .

I suppose we will just have to watch this space to see if any new research comes to light that will change the recomendations.

Linda x