Have her2+ er+ pr- bc had lumpectomy 4 x ac and 4 x th followed by 30 radiotherapy and 14 x herceptins when a scan showed more lumps in same boob 2 x lesions on liver and 1 x lesion on lung. Biopsy of boob and liver showed her2+ again so had single mastectomy and started kadcyla. Had 5 x kadcyla and a scan monday that shows the kadcyla is not working. Dont have all details yet but wondered if anyone had anything similar and what the next options for treatment might be so that I have something to ask at my appointment on friday. Thanks. Xx
Personally I don’t have any similar experience. Heard from my in-law living in the US there are a few options for treating HER2+ metastatic bc. ps. I am not any medical
Herceptin + Purjeta
Kadcyla (which, you already have it)
Neratinib + Xeloda ( a newer treatment approved recently)
Lapatinib + Xeloda (an older treatment)
By the way, look like your primary treatment is adjuvant. Did your first after treatment scan was taken before radiotherapy or after ? At that time, have you started the hormone therapy ?