Letrozole and incontinence

hi everyone, my first time here. I have been on Letrozole for 3.5 years after a lumpectomy. I was first prescribed a generic brand and suffered dreadfully for 2yrs with chronic aches and pains. I couldn’t bend and going downstairs a nightmare. Dizziness and lack of balance finally made me connect the pills with these symptoms. I also had an X-ray of my right hand and it turned out I had severe degenerative arthritis in one finger and mild to moderate in the rest. My Onc nurse suggested I ask my GP for Femara and I was able to get it. Since then without the chronic aches and pains to distract me I noticed I couldn’t seem to hold my urine. Over time it got worse and embarrassingly worse. Again it took some time to connect this new occurrence with the pills but eventually losing control a few times in public and the soggy piles of washing and the moping up of the bathroom floor made me ring my Onc nurse. She was a bit disbelieving and suggested some pills and exercises. However, I had googled this and my symptoms were not so common side effects in the UK but common side effects in Canada. At my insistence, because I wasn’t imagining the increase in intensity, she suggested I had a break from the pills to see if there was a difference. Well, dear readers, that was 3 wks ago and I am very happy to say my bladder is now back to normal. I have been offered tamoxifen honestly I’d rather put up with the bladder problems than have aches and pains. Better the devil you know

Hi Bubbles, 

I am sorry you are going through this difficult time and I am sure some of our users will be along soon to share their experiences and support.

If you are based in the UK please do call our support line on 0808 800 6000 who will be able to talk to you about Letrozole and offer a friendly ear. This is open 9-5pm Monday - Friday and 10-2pm Saturday. 

If you are based elsewhere you can call the support line on (+44) 20 7620 0077 but unfortunately we are unable to offer this as a free service.

Best wishes,

Lizzy

Digital Community Assistant  

I have been on letrozole for 9 months with just a few niggly side effects from time to time.  Nothing too dramatic.  I have however had urinary incontinence which has got worse recently.  I have had to resort to Tena lady and wet myself several times a day.  The urge is sudden and beyond my control.  Today I wet myself in the library this morning and again in the hallway when I got home.   I shall be seeing the surgeon in a few weeks so I’ll bring it up then.

Good luck.

I had a spell of urinary incontinence maybe two years before I was dx’d w/ CA. After being on Letrozole 3 years or so, it came back w/ a vengeance. I am wearing maximum strength Depends, to stay dry, but I still have accidents. 

 

W/ my oncologist’s permission, I went off the Letrozole 5 days ago. The chronic back pain that I thought was due to it is easing. Much to my surprise, the incontinence scaled back a lot, too. If this continues, I may be able to wear only a pad or even REAL UNDERWEAR!!!  Excitement!

I haven’t heard of that side effect just that the reduction of oestrogen can increase urinary tract infections. I haven’t become incontinent yet but if I do, I shall go off it.

Seagulls

Well ladies you have all made me feel a lot better.

I have incontinence and like you have been having frequent accidents. I didn’t even consider that it might be a side effect of Letrozole.

ok so I will contact the breast care team and get their advice.