Letrozole or Tamoxifin

Living with secondary breast cancer Treatments and medical issues
1

Hello

I would like to ask is there a preference between letrozole and tamoxifin? I have been on iv paclitaxol have 4 more weekly sessions so at the end would have completed 6 months in total. Following scans everything is stable and tumour markers reduced from 243 to 177 this week. The lowest has been 164 but always goes up a little on my week off. Following oncologist appt the plan is to put me onto letrozole or tamoxifin and he says it’s my choice……he has provided a leaflet on each tablet. 

Could anyone help with the best one to start with? Ideally I would like the tablet to keep my cancer stable, Shrink if possible. Is there anyone on either drug and has it worked and for how long?  I was on tamoxifin with primary BC for 1 year but they changed to exemestane, because it had better results, so I can go back on tamoxifin.

Thanks for advice and wish everyone well.

Louise  

2

Hi Louise,

Im in the same position, have my last Paclitaxel this week ( number 18) then if all stable can go onto an anti hormonal tablet. I believe that tamoxifen benefits pre menopausal more than post menopause. I’m 62 so will go with Letrezole. If you are pre menopause maybe go with tamoxifen as you can keep Letrezole in your back pocket.

Im wondering how long either of these will hold back the cancer for? Would love to hear of anybody in a similar position to us who got some good results.

Take Care

Debs xxx