Im interested to hear if anyone has had any luck taking Capecitabine for ER positive HER2 negative liver mets?
I was diagnosed with liver nets in June and prescribed letrozole, zoladex and palbociclib.
I found out yesterday that this regime hasn’t worked for me.
My mets have now spread and I have numerous small areas throughout my liver. ?
I’d like to know if Capecitabine has worked for anyone else when oestrogen blockers have failed. My Er level is 7 so I’m disappointed blockers haven’t touched my mets.
Thanks ladies.
Hi
Unfortunately hormone blockers don’t always work even if you are hormone positive and even those that work eventually stop being effective. I had been on hormone treatment for nearly 5 years (for bone mets) when my liver mets were found. I went onto Capecitabine and it worked very well for about 18 months. I remember at the time reading that it is usually effective for soft tissue mets so I do hope it works well for you. If you check out the XEloda/Capecitabine thread there’s quite a few ladies (maybe all?) taking it for soft tissue mets.
Nicky x
Thanks Nicky.
I’m very happy to hear it worked for your liver mets. Here’s hoping I get a good response. ?
Nerve wracking. X
Haha, thanks Kate. ?
It’s good to hear from you. I hope you’re still doing well. Xxx
Hi there, this may be late, however I’ll share my experience on xeloda. It worked great for me for about a year. I am ER positive as well and had been on arimidex and then verenzio. BY far xeloda is my favorite and I had numerous lesions on my liver. All were healed by this awesome drug. Good wishes for you and try not to fear the side effects. Your oncologist will help with that. Just stay as active as you can is my number one advice. All the best Gibbi
Thanks for this Gibbi.
Im tolerating it really well with slightly dry hands being the only side effect. My liver enzymes have came down within the normal range too, so it’s looking very positive.
Hi, my situation is just like yours and would like to hear from anyone with positive results- hormone blockers did not do a thing for me. I am on my third cycle of Caps. 1200 twice a day- my scan is next week. I do feel much better than I did before starting- the scan will tell. I will let you know next week- much luck and love to you!
Hiya Karen, nice to hear how you are, also sorry for the delayed reply, I’ve been so busy with work and other things that I haven’t had much time to come onto the forum.
Glad that you had a bit of a nice break “living normally” while they delayed your treatment, I totally get that as I often don’t mind when my treatment gets delayed by an exra week or two. How are you getting on? I am on my 8th or 9th cycle now and so far so good, working full time and also getting out for walks. I think the walking is doing amazing things for my body, I generally feel much more well than I have before on treatment, the fresh air is also great while we are all cooped up in lockdown. Glad to hear that wfh has also been good for now, I think its really important to try and have some normality. I don’t have many side effects thankfully, skin issues are my only bug bear and of course the fatigue if I over do things but on the whole its really manageable so far. Let me know how you are getting on xxx
Can I please ask what were peoples options once capecitabine stopped being effective? Has anyone been on it for a length of time as many of you have stated it only worked for a while?
Im on my first cycle after Ribociclib/letrozole combo stopped working after 3 years. No side effects jus yet and hope that continues