Hi glasgow12,
Thanks for posting.
It’s understandable that you are feeling anxious after being told that your breast cancer has changed from grade 2 to grade 3. You might find it helpful to give us a call on our helpline on 0808 800 6000, we often find we can help more by talking on the phone, the helpline team have time to listen, talk things through and signpost you to more support and information if necessary.
As @laneycass and @shelbylou81 explain, it’s not uncommon for treatment plans to change as more information becomes available, but dealing with the uncertainty that this brings can be very stressful. Oncotype DX is used when the benefit of chemotherapy is unclear. It looks at the genetics of the cancer and can help your treatment team decide whether you would benefit from having chemotherapy.
The breast contains blood vessels and other tiny tubes called lymph vessels. If breast cancer cells spread into these vessels, it’s called lympho-vascular invasion. This increases the chances of the breast cancer coming back (recurrence), but having lympho-vascular invasion is different from having breast cancer in the lymph nodes. Your treatment team will use this information, along with other information gained following your surgery, including the size of the tumour, margins and the fact that the lymph nodes are negative, in addition to the Oncotype DX score, to decide the best treatment for you. As @Shi says, you may find it helpful to write down any questions you have in preparation for your next appointment.
Talking to someone who has had a similar experience can often be helpful. Our Someone Like Me service can match you with a trained volunteer who’s had a similar experience to you. You can be in touch with your volunteer by phone or email and they can share their personal experiences to answer your questions, offer support or simply listen to how you are feeling.
We also offer support tailored specifically for younger women with primary breast cancer who are aged between 20-45 years. This includes our Younger Women Together events that are run face to face and online. This support offers the opportunity to meet and share experiences with other younger women and get expert information in a confidential space. More information can be found on the links above.
As mentioned above, do call our helpline if you would like to talk this through or have any further questions… Your call will be confidential, and the number is free from UK landlines and all mobile networks. The number is 0808 800 6000, If you have hearing or speech difficulties prefix our number with 18001 and the call will go through Relay UK. Our helpline has access to telephone interpreters if language translation is required.
If you would prefer one of our nurses to call you. To do this please complete this form ticking the box agreeing to a call back.
Our usual opening hours are Monday to Friday 9am - 4pm and 9am -1pm on Saturday.
Out of hours you can leave a message and we will call you back when we next open.
Best wishes
Katie
Breast Care Nurse
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As we are unable to monitor for further replies, this thread will now be closed. If you have any additional questions or would like to provide feedback, please start a new thread, call our helpline, email us or request a call back.
also discuss with your team too so write all your questions down so you can write answers down too so you can remember what’s been said, sending 
we got you as much or as little as you need 
