Hi
I’ve been on Letrazole for some months now and alendronic acid etc
For some reason the last couple of months have been difficult , I am nauseous every day and it’s becoming unbearable daily . My weight is dropping again , aching joint and muscles are now an issue too .
My query is , could it be the letrazole ?
Though the first few months I was fine .
Thank you for reading
Hi Catnip, I’m sorry to hear thar youve not been feeling great. Im interested to hear if you get any advice on this as, like you, i take Letrozole, have been on it since November last year, but ive found the last month or two I’ve had frequent nausea. Hope it passes soon xx
I’m on my first month if Letrozole and am definitely feeling nauseous as a result. I’m taking the tablet at nighttime and am still on omeprezole for indigestion but don’t think it’s helping this. Nausea isn’t enough to affect my daily life but does get worse as the day goes on. I didn’t find Domperidone very useful during chemo, so not really sure what else could be offered, although it’s another 6 weeks before I see my oncologist again
Hi Elsa
I’m sorry to hear you’ve experienced nausea too .
I’ve taken it now for about a year and a half and mild at first so put it down to my digestion problems which just come and go . But for the last few months it’s worse . To the point of making me not want to eat and like you it gets worse as the day goes on .
Time to see my doctor again I think as it’s really getting me down now
Hi altoan
I’ve been on it a year and a half and to be fair and at first it wasn’t an issue . Now I’m struggling with feeling nauseous every day .
Back to the doctor I think , maybe to check all my meds to confirm if it’s Letrozole causing it and not something else .
Hope you feel better soon and it calms down for you
I have not got nausea but two and a half months in I am having hot flushes and a lot of stabbing pain in my legs ankles and wrists. I also having violent mood swings. Some of these are probably related to my husband’s philanderings but not all. I didn’t have a difficult menopause at 54 in fact I sailed through it.
I now think this is because I have lots of oestrogen which helps with bone strength and keeps away rheumatism etc.
So I am seriously thinking once again to ditch the drugs and live maybe a shorter life but a better one. Old age stinks.
I saw my mother yesterday and she’s on an airbed in a room on her own with no stimulation and very infrequent visits from staff. Yes I don’t have to look after her. But no she has a pretty diabolical life and the fees are astronomical at £6450 a month.
If dignitas wasn’t so far away on an industrial estate in Switzerland I would sign up now. But that’s me not my mum who hopes to join my Dad up in heaven.
Seagulls
Like you Seagulls I haven’t had nausea but I reckon I’ve had every other side effect in the book and after seven months I am so fed up with it. I’ve gone through the should I stop/should I struggle on malarkey so many times but yesterday after an awful week with them I said no. I’m not sure I’ll stay off them permanently or just for a while but I see my surgeon in 7 weeks and he said originally he didn’t think I needed them but it was up to the oncologist and I felt that she just doled them out to everyone. So for now those evil little yellow pills are banned and this morning I went out for an hours walk in the lovely autumn weather, I could not have done that yesterday. At 78 I’ve chosen a happy, blessed life over becoming a miserable old crone.
I would back anyone 100% on whatever decision you make, you must do what’s right for you. Oh and I forgot a friend who started Letrozole at the same time as me has had no side effects at all - explain that one.
Love to you all x
EVERY DAY IN EVERY WAY WE ARE STRONGER 
I felt nauseous for first few weeks but only occasionally now . I’m in Anastrazole but it has the same effect on oestrogen I.e annihilate it !
It’s a common side effect.
Oestrogen affects all our bodily functions , so it makes sense that a lack of it affects your digestive system .
Oncologist asked GP to prescribe Amarox as I seem to tolerate that better .
Can you ask to change brands ?
Good points , I think I need to get onto my nurse team