Palbociclib problem

I have been on Palbociclib 125mg since October 2020. Over the last 6-9 months, once I start taking it after the 1 week break, I have excruciating stomach pains for 3 days. Any advice about why this might be or what might help?
Thank you!

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Hi louises46

Thanks for posting.

Unless associated with diarrhoea, abdominal pain isn’t a commonly reported symptom of palbociclib.

You don’t say whether you have discussed the symptoms you experience for 3 days at the beginning of each cycle with your treatment team, specialist nurse or oncology pharmacist. We’re unable to offer medical advice as we can’t say what may be causing your pain. It’s important for you discuss your symptoms with your team so this can be investigated.

You can call our helpline if you would like to talk this through more or have any further questions. The helpline team have time to listen, talk things through and signpost you to more support and information if necessary. Your call will be confidential, and the number is free from UK landlines and all mobile networks. The number is 0808 800 6000, (Relay UK -prefix 18001).

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Best wishes


Breast Care Nurse

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