Palbociclib

Still here ,thanks for that. I’ve never had a flu jab in my life, so yes I’m worried I could have a reaction. You have been helpful, I went through where I go & how I make sure I have my sanitizer, friends avoid me or tell me to stay away if they aren’t well,which is sensible. My wife has had her flu jab, which my oncologist said was more important, because if I was going to catch it from anyone it would be her. My gut feeling is saying not to have it. You said you’re on your 33 palbociclib, that’s brilliant & encouraging . Thanks for your help it’s much appreciated x

Hi mags.
I had mine two weeks ago, then three days later flew to Spain. No problems at all. My oncologist advised me to have it on my week off the meds.
Hope you’re doing well.

Hi feelthefear, I hope you had a cool time in Spain. I decided not to have the flu jab, touchwood still doing ok. When I was at my secondary group pain management palliative nurse said if I’ve never had flu or bad colds & more important my wife has it not too. So I’ll make sure I keep away from hidden dangers as best I can. I think if it was already in my system before my cancer came back I would have had it x

Hi. 

I am interested to know if anyone on here is doing a different palbocyclib schedule to the 21 days on 7 days off. I know there is currently a trial in the US seeing if a continual 5 days on 2 days off works better to reduce neutropenia, which will report on its interim findings next year.  I started on Palbo 13 months ago and had the dosage reduced to 100 after about 5 goes, because my neutrophyls were consistently low.  This last cycle I have been feeling grotty nearly all the way through rather than just at the end. I had a FBC blood test (for the dentist) on day15 and they were already only at 1.13.  I will ask my oncologist what she thinks about changing the schedule, but tbh I dont have much faith in her,  so am thinking of trying the 5/2 one for a month anyway to see if it improves things.

 

Thanks

Sally

Hi Sally, I’m not a big help because I’ve never been on a different cycle to the 3 on/ 1 off. Luckily, after 33 cycles I haven’t had to miss any weeks apart from a bad flu last January.

What I was going to say is that I have read anecdotal evidence on a U.S. Forum that reducing the dose further to 75mg has still given good results. They have been using Palbociclib for much longer than us so it might be worth a discussion with your Onc? 

Im on imbrance, zoladex n letrozole, hot sweats coming thick n fast feel very tired, n itchy, but so sickness. Secondary breast after 10 years. Such a shock. On the tumeric lemons vit c to keep me bug free, that n garlic n good foods. My white cells are a bit low at 1.98 but higher than the first round, just finishing my second round tomo. Fingers crossed they stay level. PMA all the way ladies. Much love

Im 43 and on the same. Hot sweats make me feel like my heads gonna explode lol.
Im positive and i keep tabs on coppafeel founder kris. She is 10 years in with secondary. So there is hope, n medicines keep getting better. Lets stay strong togther. Much love