Hi ladies, just finished 2 cycles of parp trials and sadly not worked. Was hoping for a good result (am triple neg and brca1) but it wasn’t to be. Didn’t have a good result from
Capecitabine before that either so now it’s onto gemcarbo. Anyone had any good/bad experiences on this? They say no hair loss but am a bit worried as I seem to be the exception to the rule on everything 
I am so sorry to hear that. I have started PARP tablets recently. Its so scary. Anyway hope the next treatment works.xxx
Really sorry to hear the parps have failed you 
They really are hit and miss when it comes to their effectiveness but you did right to try them. The gem carbo regime is very common + widely use in the States too. I’m just on carboplatin + have had good scan results so far. It’s been an easy chemo, no hair loss + minimal s.e.'s. Combining carbo with gem makes things a little tougher I believe. The regime is tough on blood counts + I know a few ladies who have found it very hard going- but effective in either stabilising or reducing their mets. You won’t lose your hair which is a bonus- mine is thicker than ever.
All the best
tina x
Hi Frances
I had Carboplatin with Gemcitabine last year and it worked very well - significant reduction, so I was very pleased. I did have a bit of hair thinning but, as I have quite thick hair to start with, it wasn’t noticeable to anyone other than me and my hairdresser. One year o from that treatment ending and I have had lots of re-growth again.
Yes, it is tough on the old blood count but I didn’t feel as unwell as I did on my first chemo with Taxol and FEC (Trial). I did have a Hickman line put in to help but it was a disaster as there was some bugs in it more or less from the word go and I had problems with being neutropenic until they took it out. I was fine after that.
Hope this helps and good luck. Sue x
Thanks for the advice, I have a portacath anyway from the parps which makes things soooooo much easier!