I started in September and had to split into half twice a day as it made me so buzzy at first.
I understand it takes a couple of months to build up and it did settle down (obviously other side effects arrived) but I carried on.
I started taking it in one dose in the evening about 5 weeks ago and at first noticed nothing different. But then gradually started having issues with water retention, especially feet.
It could be coincidence as my periods have clearly started to return and I think I need a thyroxine review but I reverted to half in the morning and half at night yesterday and do feel much better this morning. (I also doubt it would happen that quickly!)
Has anyone found some side effects are easier with splitting the dose? I’m going to persevere but admit once. Day was easier to remember!