Hi I took anastrazole for two years and exemestane since January. Also changed my antidepressants from sertaline to mirtazapine.
I still feel so crap, I’ve no energy, never had anxiety and depression last 7 months, I don’t want to go out. I don’t know why I can’t get a grip on things. Im 52 married with two children 2 grandchildren and should be enjoying life but I’m not I’m just exsisting. Im giving up work as I just don’t have the energy to carry on. Im scared to go to doctors incase he suggests blood tests, I can’t cope with the phone call with results and the waiting(not that I need blood tests) but frightened of what they might say. One wrong word sends my anxiety soaring and I’ll go to pieces. I honestly think nothing can be done to help me. I just want to feel like me again ? as this is unbearable. Im currently on a break to see if my ovaries have packed up so I can stop the zolodex. Should I try another hormone tablet or go back to anastrazole as the thought of starting exemestane again scares me. Sorry to whine on but I feel so low and exhausted. Xxx
I have no experience of the medications you are currently on, but I do/did of tamoxifen…and it made me feel so emotionally, physically and psychology unwell that I was taken off it and advised I would need mental health input daily if I was going to take it again. (I was unusual in such an extreme response)
I sense shades of my emotional state during those weeks (and yes, I only managed weeks!) in the words you are writing. Something isn’t right for you, nobody should be living like this with a low quality of life - or as my onc said at the time - when you are taking medications you expect some side-effects, but if the balance shifts and you have no quality of life, then its time to take action. ‘Just existing’ isn’t enough, you don’t deserve that. Not everything works for everybody, not everyone gets away with no side effects or just a few manageable side effects…some people are unlucky.
There was no ‘decision’ for me make really - it was obvious that I couldn’t continue as I was. I can see that for you they are trying adding in an AD and have changed to exemestane and seeing if you are through meno with stopping the zoladex, but you still feel no better. Sooo…
I am not a medic, and I’m also loathe to say anything that affects your personal decisions, because those choices are between you and your doctor/s - but I would advise a candid and honest talk with the healthcare provider currently tasked with your prescription. You must state how your mental state is right now, as you have here. This is horribly miserable. I empathise and sympathise hugely, and I am more than happy to keep replying to you on here, but I do feel its time for some ‘quality of life’ discussions. There are some complex factors here - such as - your original diagnosis, how much you feel pressured to continue with the current situation by others, how much you feel you are better psychologically knowing you are taking the exe., and if there are other routes that could be explored before taking more radical action. You need some opinions and some discussion - do remember there is the helpline on this site where impartial conversation can take place 
Do let me know how you get on x