Just wondering if anyone gets tingling in arms and legs/ feet whilst on Letrozole ?
I did with Anastrozole. The leg tingling has generally stopped now and wearing a wrist splint at night a few times a week (I tend to alternate wrists) has stopped the wrist tingling.
Remember, if it’s bothering you, ask your BCN or GP.
Hi irenest
Thank you for your question.
We’re often asked about side effects of letrozole. Carpal tunnel syndrome is pressure on a nerve in your wrist. This causes pain, tingling and numbness in your arm, hand or fingers. As @elsie1 says using a wrist splint can help. Sometimes it can go away on its own, but it can take months to get better.
Joint and muscles pains are common side effects of letrozole. Joint symptoms can interfere with your quality of life and you can speak with your treatment team or GP if these side effects are difficult to cope with.
When side effects are severe, you may be asked to stop taking letrozole for a short period of time to see if your symptoms improve. Sometimes they may suggest changing to a different aromatase inhibitor drug to see if that suits you better. If there is no improvement you may be recommended a different hormone therapy, tamoxifen which has fewer joint-related side effects. Your treatment team will be able to talk to you about the benefits of doing this.
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