Using Ovestin

I had mastectomy and chemo in 2007 my cancer was oestrogen based
Recently I’ve had a donut pessary fitted, due to a prolapse, which is being changed 6monthly, I’ve been advised to use Ovestin twice weekly to help with any infection or soreness that could occur.
With the type of cancer I had, although I have been reassured, I feel a little apprehensive about using it as anyone come across this worry and is there another option

Hi @aileen1 if your cancer was Er+ you should be on endocrine treatment, either Tamoxifen or an AI such as Letrozole or Anastrazole. If you are on Tamoxifen, using Ovestin should be fine as the small amount of Estradiol in topical treatments does not cause or feed BC tumours.

I had suspected vaginal atrophy when I started Letrozole and was prescribed Vagifem pessaries by my oncologist but had to swap to Tamoxifen. In the end it was vaginal dryness so I chose to control it with Hyalofemme cream and went back to Letrozole as it is a more effective treatment for my age (68).

Check with your BC nurse or oncologist but I think it is commonplace these days to have topical vaginal oestrogen coupled with Tamoxifen. As an example, the BC surgeon Liz O’Riordan uses both. She has done a couple of videos on it on YouTube if you’re minded to look for them.

Hi aileen1

Thanks for posting. It can be difficult when you are advised to use a treatment that you are unsure of, and it’s understandable you feel a little apprehensive.

Although as @Tigress has said it is safe to use Ovestin alongside tamoxifen, it is unlikely you will still be on any hormone (endocrine) therapy as your breast cancer was diagnosed in 2007.

The best people to talk to about your concerns are either your treatment team if you still have any contact with them, or your GP.

You may find it helpful to read our information on coping with vaginal soreness and what other options may help. If you do have any symptoms of an infection such as an unusual discharge do contact your GP.

Although you were diagnosed many years ago you may be interested in our range of free supportive services for anyone who has had a diagnosis of breast cancer.

Do call our helpline if you would like to talk this through or have any further questions. The helpline team have time to listen to your concerns, talk things through and signpost you to more support and information. Your call will be confidential, and the number is free from UK landlines and all mobile networks. The number is 0808 800 6000, (Relay UK - prefix 18001).

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Best wishes


Breast Care Nurse

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