Hi Pink Princess 81
This was a topic that was discussed a couple of months back and I have posted the reply that Sam, BCC gave us which should help answer your question. As she says, the best person to discuss why you are being given your particular treatment regime is your oncologist.
Sam BCC says on 29 Nov 2011 15:53
I am making this post on behalf of the clinical team:-
Hi everyone,
With regard to ‘libsue’s query about why some people are put on EC or FEC for three cycles and then Docetaxol for three, and what the advantages are of using both prescriptions.
You’ll all know that chemotherapy is a treatment using anti-cancer drugs. Their aim is to destroy breast cancer cells. It’s known as systemic treatment because the whole body is exposed to drugs. Various factors are taken into consideration when deciding on whether or not to recommend chemotherapy in the first place and if chemotherapy is recommended which type of drugs would be best to use. These factors include, for example, the size of your breast cancer, the grade and whether the lymph nodes under the arm are affected. Also your general medical health and any other medical conditions will also be considered.
There are many different types of chemotherapy drugs used to treat breast cancer. They can be given in different ways and also in different combinations, according to your particular situation.
The way chemotherapy works is that it interferes with the way cancer cells grow and divide (the cell cycle). Using different chemotherapy drugs in combination will interfere with the cell cycle at different phases of its growth.
That is why a combination of drugs is used.
The NICE (National Institute for Health and Clinical excellence) guidelines recommend that chemotherapy after surgery for breast cancer should consist of 4-8 cycles of a combination of drugs, including an anthracycline (epirubicin or doxorubicin). NICE have also approved docetaxol (Taxotere) after surgery for women with early stage breast cancer who have lymphnodes under the arm that contain cancer cells. In 2009, a review of chemotherapy trials for early breast cancer found that adding a taxane based chemotherapy regime to anthracycline chemotherapy seems to reduce the risk of the cancer coming back more than using anthracyclines alone.
It’s important to remember that everyone’s cancer is individual to them, and therefore treatments will vary. Oncologists will weigh up the benefit (or additional benefit of different drugs) of chemotherapy versus the side effects before making any of their recommendations.
Do talk to your specialist team if you are unsure about the combination of chemotherapy drugs that you’ve been offered.
Best wishes Sam, BCC Facilitator