Zoladex and Exemestane

Hi ladies, 

I have just been switched from Tamoxifen to  monthly Zoladex and Exemestane with a view to removing my ovaries in a few months… I am looking for other people’s experiences of this combination,  side effects,  length of time, before they settle, etc. Can any ladies let me know how they find  this treatment?  I have had a mastectomy, FEC-T and Herceptin which I was unable to finish due to my ejection fraction falling. Many thanks in advance. :-) 

Hi, I am on thjs combination but a newby. Had my first injection a month ago, it did not hurt!! Started tablets a week ago and I don’t want to tempt fate as it is very early days but so far okay. I asked for them to remove my ovaries as I did not want to be on a whole batch of drugs, but they won’t consider it until things have settled post op and radiotherapy and oncologist indicated it might be up to a year before they did. I hope all goes well for you and will read the other posts with interest, thanks for starting it ?

Hope it’s Ok to join in this conversation. I am also on both zoladex and exemestane, half way through 4 1/2 weeks of radiotherapy. Seem to be having very similar experiences to you all. Also put on about a stone and a half, this is also due to comfort eating and not doing exercise that I was doing before and giving up smoking! Do you think it makes any difference when you take the exemestane to what side effects you get? :slight_smile:

Hope it is Ok to join this conversation. I am also using both exemestane and zoladex, and have 2 more weeks left of 4 1/2 weeks of radiotherapy. I seem to be having very similiar side effects. Does it make any difference to what time you take the exemestane to the side effects you get? :slight_smile:

Thank you for your comments, i am feeling a bit overwhelmed by all the side effects but the worse is the bone aching. This is all so new, no crochetgirl am not taking herceptin. Got 2 more weeks of radiotherapy and then will start to try and exercise again but too tired at the moment. x