Ozempic, Wegovy, Mounjaro: Has anyone tried these?

I’m not sure where to post this really. I was diagnosed with ER/PR+ HER2- Breast Cancer in June 2022 and am now on Letrozole, Zoladex and Calci-D to support my bones. The thing is, I’m now back to the heaviest weight I’ve been after having lost weight during my treatments and I’m honestly scared that it’s increasing my risk of recurrence or metastasis. I’ve have tried dieting and exercise but the weight doesnt seem to budge. I know someone who is having amazing results using Mounjaro after many years of weight fluctuations and I’m really interested but I’m wondering if anyone else has had these types of treatment approved by their oncologist post Breast Cancer?

I dont want to ask the question to my Oncologist without asking here first because I get the distinct impression from my Oncologist that they’re a bit old school about things. For example when I mentioned my frequent hot flushes his suggestion was to try Evening Primrose Oil but then I saw so many people here talking about things like Gabapentin. On the other hand when I mentioned frequent UTIs and that I was trying D-Mannose he seemed to not really be that supportive.

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I can’t help you with your query - I’m in a similar position to you as regards weight but I’m very reluctant to try a weight loss drug. I do know people who are on them and doing well in themselves and have lost weight . My friends brother was on one of them ( he’s diabetic ) and had a dangerous episode of hypoglycaemia . As regards interactions with cancer medication or how they would affect the risk of recurrence I’m not sure that anyone could say for sure as they are so new that it may not have been studied at all though losing weight is obviously beneficial. I’ve read a post on here from someone saying that Oncologists are pretty conservative even by medical standards and you can see why really - may not even have heard of DMannose for example . I remember mentioning that to my GP on the phone and he said “What?” so I repeated it and could hear him furiously googling in the background .

It might be a good idea to speak to your GP about them or your BCN who may be able to make inquiries of a friendly Pharmacist ( one did this for me re something ) or they might take it to your Oncologist in your behalf. The Nurses on the helpline here may also have more information for you. Xx

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Agree with Joanne speak to your doctor or team about that to ensure it will be safe for you and any risks it could involve to you :two_hearts::two_hearts::sparkles::sparkles:Shi xx

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Hi, I was on Wegovy and Sandrena hrt gel prior to the diagnosis (12 Nov 24) ER and PR+. I was told I had to stop Sandrena immediately. I was booked in for double mastectomy and diep flap reconstruction 5 Dec 24, but got covid at the end in Nov. my surgery got put back to 19 Dec, and I was told to stop Wegovy 3 week prior (as anaesthetists can be abit funny about it). Post surgery as a result of the tumour size being greater than double the initial size (30mm) I was told I would commence chemo (TC) 6 Feb 25. My oncologist said I could recommence Wegovy a couple of weeks prior to this date. My GP said to recommence on .5, she said Wegovy supported, in particular the reduction of peri menopausal weight gain especially as I can no longer have Sandrena. I start my second chemo cycle next week.
I am from England but live in Melbourne, Australia. The medical systems are very very different. Hopefully you get the support and answers you want and need.

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I’m currently on Wegovy, and going through radiation. I’ll be starting letrozole at the end of the month. I discussed my concerns with my doctors and they all think staying on the wegovy while taking letrozole is actually a good idea. They said Wegovy is actually good for any cardiac issues that could arise. This may not apply to you but because I have high blood pressure, I was very concerned about the effects of the letrozole on my heart.

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That’s good to know @brett . Xx

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